Scientists have uncovered the path to a longer, healthier life. And what is happening is real estate is fascinating. Take a look…
Path To A Longer, Healthier Life
September 5 (King World News) – Gerald Celente: Researchers at the University of Connecticut have identified a protein known as p21 as a key culprit in aging and the illnesses and general debilitation that can accompany it.
As we age, cells that make p21 multiply in our tissues. In a study with mice, scientists periodically cleared away those cells. That process extended the mice’s lives by an average of 9 percent, equivalent to seven human years.
To simplify the experiment, the scientists engineered flocks of mice with a genetic switch that, when turned on, would cause the cells making p21 to self-destruct.
When the altered mice reached an age equivalent to about 60 or 65 human years, the researchers began giving them a monthly dose of tamoxifen, a drug that blocks estrogen production and is used to treat breast cancer.
The tamoxifen activated the genetic switch and cells producing p21 gradually died off.
The treated mice not only lived longer, but also had better grip strength, walked faster, and showed less frailty than mice who received the same doses of tamoxifen but lacked the genetic switch. The altered mice had better heart health, healthier livers, and better blood sugar levels. The youthful effects lasted nearly until the treated mice died.
The researchers believe eliminating p21 removed a key cause of generalized, low-grade inflammation, which has been identified as a cause in a range of illnesses associated with aging.
TRENDPOST:
Obviously, it’s not practical to adjust every human’s genome to end the production of p21. The test was meant to demonstrate the protein’s effect on aging and what can happen when it’s eliminated.
Science can now be looking at drug formulations that can eliminate the production of p21 or neutralize its effects. Some researchers will be assessing substances the body already makes that could be enhanced to provide the same effect.
This new approach to abolishing age-related illness and deterioration will draw focus and funding. Human clinical trials related to removing p21 or neutralizing its effects should be ready by 2030…
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Real Estate
In July, the number of closed home sales rose 1.3 percent from June, reversing a four-month trend of decreasing sales, the National Association of Realtors (NAR) reported.
Sales and home prices both increased most in the U.S. Northeast.
However, the figure was still 2.5 percent below the number of closings in July 2023 and the fewest sales in any July since 2010 during the Great Recession, according to The Wall Street Journal.
Also last month, the number of homes on the market rose to 1.33 million, a 0.8-percent gain compared to June and 19.8 percent more than a year earlier.
That represents a four-month inventory; a six-month supply of homes for sale represents a balanced market in which buyer and seller have equal negotiating power, the NAR says.
“Consumers are definitely seeing more choices and affordability is improving due to lower interest rates,” NAR chief economist Lawrence Yun wrote in a statement announcing July’s results.
However, “despite the modest gain, home sales are still sluggish,” he noted.
Home sales always are strongest in warm weather, but this year’s selling season has been “a flop,” according to the WSJ, as high interest rates and high home prices combined to keep a large share of buyers out of the market.
The average selling price of a home in July was $422,600, slightly down from June’s record but still 4.2 percent higher than a year earlier.
The average national Interest rate on a 30-year, fixed-rate mortgage dipped below 7 percent this month and stood at 6.46 percent on 23 August, according to the Federal Home Loan Mortgage Corp.
All-cash sales made up 27 percent of transactions finalized in July. The number in June was 26 percent. Both are well above historical norms.
First-time buyers accounted for 29 percent of sales, the same number as in June. The typical proportion before COVID was 40 percent. However, rising prices and climbing interest rates have shut out a larger number of potential home buyers.
With interest rates coming down and more houses on the market, more buyers are venturing into the market. The number of requests for viewing and other services from brokers rose 4 percent during the week ending 17 August, according to online brokerage Redfin.
TREND FORECAST:
Lower interest rates will bring more potential buyers into the housing market this fall. However, that additional demand will keep median home prices from falling by any meaningful amount.
When mortgage interest rates fall below the psychologically important milestone of 6 percent, enough buyers and sellers will become active to affect home prices materially but still not enough to drop prices far below their current levels.
History has shown that once home prices rise, they fall greatly only during the worst of economic crises.
The facts are in the numbers. Today S&P CoreLogic Case-Shiller U.S. National Home Price Index reported that despite the high mortgage interest rates, on a three-month running average that ended in June, home prices increased 5.4 percent compared to June 2023.
Gold & Silver
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